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rel-PROTAC PARP1 degrader is the relative configuration of ROTAC PARP1 degrader (HY-114324). ROTAC PARP1 degrader is a PARP1 degrader based on MDM2 E3 ligand.
Induces significant PARP1 cleavage.
Induces programmed cell death.
Inhibits MDA-MB-231 cell line with an IC50 of 6.12 μM at 10 μM within 24 hours.
For research use only.
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Medchemexpress,HY-101445 500mg Trolox CAS:53188-07-1 Formula:C14H18O4 Troloxa is a cell-permeable and water-soluble vitamin E analogue and is a powerful antioxidant. Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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RI-AG03 acetate is the acetate of RI-AG03, an orally active and BBB-penetrable Tau aggregation peptide inhibitor. It inhibits Tau aggregation and improves associated neurodegeneration and behavioral phenotypes in both in vivo and in vitro models. This product can be used in the study of tauopathies such as Alzheimer's disease.
Orally active
BBB-penetrable Tau aggregation peptide inhibitor
Inhibits Tau aggregation
Improves associated neurodegeneration and behavioral phenotypes in both in vivo and in vitro models
Can be used in the study of tauopathies such as Alzheimer's disease
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LSD acetate is a peptide that specifically recognizes the lymphatics of C8161 melanoma, but not the lymphatics of normal tissues or tumor blood vessels. When conjugated with a proapoptotic peptide, it can reduce the number of tumor lymphatics. It can be used in the research of targeted therapy and diagnosis of tumor lymphatics.
Specifically recognizes lymphatics of C8161 melanoma.
Does not bind to lymphatics of normal tissues or tumor blood vessels.
Can reduce the number of tumor lymphatics when conjugated with a proapoptotic peptide.
Useful in research for targeted therapy and diagnosis of tumor lymphatics.
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CIGB-300 acetate (P15-Tat acetate) is an anti-casein kinase 2 (CK2) peptide that exhibits anticancer properties by interfering with the phosphorylation of protein kinase CK2. It induces apoptosis in multiple tumor cell lines and can be used in cancer research.
Pro-apoptotic peptide
Interferes with protein kinase CK2 phosphorylation
Induces apoptosis in multiple tumor cell lines
Suitable for cancer research
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DL-alpha-tocopherol is the racemic (±) form of vitamin E used as a lipid-soluble antioxidant in biological research. It scavenges free radicals and protects cell membranes from oxidative damage, and is commonly used in cell-based and biochemical assays to study oxidative stress and cytoprotection against UVB-induced injury.
Acts as a lipid-soluble antioxidant protecting membranes from oxidative damage.
Protects human skin fibroblasts against UVB-induced cytotoxicity.
Provided as a ready-to-use DMSO solution for cell and biochemical assays.
High purity suitable for research applications (≈99.8%).
Soluble in organic solvents such as DMSO and insoluble in water.
Molecular weight 430.71 g·mol⁻¹; CAS 10191-41-0.
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α-Vitamin E (Standard) is the analytical standard of α-Vitamin E, intended for research and analytical applications. This naturally occurring form of vitamin E, also known as (+)-α-Tocopherol, is a potent antioxidant. This product is for research use only.
The compound is an analytical standard, commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC, and MS.
Appearance: Viscous liquid
Color: Light yellow to yellow
Structure classification: Phenols, monophenols
Initial source: Endogenous metabolite
Shipping: Room temperature in continental US; may vary elsewhere.
Storage: Store under recommended conditions in the Certificate of Analysis.
Purity: 99.58%
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Vosoritide acetate is a natriuretic peptide receptor 2 (NPR2) agonist that promotes bone growth by acting on the proliferation and differentiation of chondrocytes. It is for research use only.
Decreases NPR2 phosphorylation in chondrocytes.
Improves chondrocyte differentiation and increases growth plate area.
Reduces ERK1/2 activation in growth-plate chondrocytes.
Improves skeletal parameters in Fgfr3 gain-of-function mutation mouse model.
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