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Carboxylesterase 1 is a member of a large multigene carboxylesterase family. These enzymes are responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolyze long-chain fatty acid esters and thioesters. This enzyme is known to hydrolyze aromatic and aliphatic esters and is necessary for cellular cholesterol esterification. It may also play a role in detoxification in the lung and/or protection of the central nervous system from ester or amide compounds.
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Vitamin K2 or menaquinone (MK) is a type of vitamin K found in animal and fermented food products. Menaquinone-4 (MK-4) is also known as menatetrenone. It is common in the human diet which is produced by bacterial conversion of vitamin K1.
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Goserelin acetate is a synthetic GnRH (gonadotropin-releasing hormone) agonist peptide supplied for research use in studies of hormone-dependent cancers and reproductive biology. The acetate salt is formulated for laboratory assays and preclinical work where a defined GnRH receptor agonist is required.
High reported purity (99.87%) suitable for research applications.
Well-characterized molecular formula and weight for identity confirmation.
Supplied in small milligram quantities for laboratory experiments.
Appropriate for in vitro and preclinical cancer biology studies.
Datasheet and handling instructions available for proper storage and use.
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Tocopherol (vitamin E) is a lipid-soluble antioxidant found in whole grains nuts andnbspoils. It is known to scavenge reactive oxygen species by interacting with lipids duringnbspoxidative stress.Tocopherol-(phenyl-13C6) is an isotope of vitamin E wherein all the six phenyl carbons are replaced by 13C6 carbon.
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SCH900776 S-isomer is a small-molecule inhibitor targeting checkpoint kinase 1 (Chk1) It is designed to inhibit Chk1 kinase activity thereby interfering with DNA damage-induced checkpoint responses and disrupting S-phase cell-cycle arrest SCH900776 S-isomer exerts its biological activity primarily through selective inhibition of Chk1 kinase (IC50 3 nM) with substantially weaker inhibition toward Chk2 (IC50 1500 nM) and CDK2 (IC50 160 nM) In cellular assays treatment with SCH900776 S-isomer mimics the genetic depletion of CHK1 by RNA interference Based on these pharmacological properties SCH900776 S-isomer holds research potential in oncology particularly in combination with DNA-damaging chemotherapeutics to study enhanced cytotoxicity and altered cell-cycle progression in tumor and leukemia cell lines
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